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At InterSystems, we deeply appreciate the rapid innovation enabled by open-source development. Our team acknowledges the significant impact of the community's dedication, which has been a driving force behind the evolution of software and data technology.

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iris-medmatch

An AI-powered patient matching engine built on InterSystems IRIS, utilizing Vector Search and Natural Language Processing (NLP) to find clinically similar patients across FHIR repositories

Ashok Kumar T
Docker
Python
5.0 (1)24 Feb, 2026 98

iris-CliniNote

Modern clinical documentation platform for tracking patient episodes and detailed notes with semantic search capabilities.

Muhammad Waseem
Docker
IPM
AI
5.0 (1)26 Feb, 2026 109

InterSystems Ideas Waiting to be Implemented

IRIS and ZPM(Open Exchange) integration

Is it possible to integrate IRIS admin panel and OpenExchange, so people could see and install the apps just from there? Like you can install plugins in other products.

E
by Elena E

14

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4

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Iris Global Guard AI

AI powered analysis tool for Global storage risk management

Docker
IPM
AI
0.0 (0)23 Feb, 2026 230

withLove

An AI-Native Low-Code platform for InterSystems IRIS. Build UIs, REST APIs, SQL Schemas, and FHIR Integrations using natural language agents. Zero boilerplate, pure creation.

Docker
IPM
AI
0.0 (0)11 Mar, 2026 187

facial-matching

Register and validate people using facial recognition

Yuri Marx
Docker
Python
AI
ML
ML
5.0 (1)28 Feb, 2026 111

Vector-inside-IRIS

run vector search inside IRIS

Robert Cemper
Docker
5.0 (1)25 Jan, 2026 337 1

geo-vector-search

mathematical use of vector search

Robert Cemper
Docker
5.0 (3)25 Jan, 2026 397

dc-mais

Multi-Agent Interoperability Systemis an agentic micro-framework

Henry Pereira
Docker
Python
IPM
AI
0.0 (0)25 Jan, 2026 53 1

FHIR-AI-Hackathon-Kit

A kit for using IRIS with Python to create FHIR applications with AI

G
Gabriel Ing
Docker
Python
AI
0.0 (0)16 Jan, 2026 35

iris-health-fhir-agentic-demo

Event-driven Agentic AI demo for healthcare using InterSystems IRIS for Health and FHIR

A
Alberto Fuentes
Docker
Python
AI
5.0 (1)09 Jan, 2026 76

iris-vector-search

Quick and easy ways to use iris vector search with Python.

F
Fan Ji
Docker
AI
ML
ML
4.3 (3)06 Jan, 2026 2.0k

iris-pgwire

PostgreSQL wire protocol server for InterSystems IRIS - Connect any PostgreSQL client to IRIS

Thomas Dyar
Docker
Python
0.0 (0)26 Dec, 2025 30

IRISVectorSearchRAGExample

Example of RAG using IRIS vector search

E
Emil Polakiewicz
Python
AI
0.0 (0)08 Dec, 2025 56

VIPIK

Hackathon

Y
Yannick Daniel Gibson
Docker
Python
AI
ML
ML
0.0 (0)03 Dec, 2025 57

FHIR SQL Builder with Vector Search

FHIR SQL Builder with Vector Search Demo

F
Fan Ji
Docker
Python
AI
5.0 (2)22 Nov, 2025 91

DevHub

a centralized toolkit and launcher framework designed for Devs

Ashok Kumar T
Docker
IPM
5.0 (1)31 Oct, 2025 151

inquisidor

Tool for public tender analytics

Luis Angel Pérez Ramos
Docker
Python
4.5 (1)23 Oct, 2025 88

IRIStool and Data Manager

This is a POC to demonstrate how InterSystems IRIS can be integrated with pandas and plotly Python libraries via the Python SDK (IRIS Native).

P
Pietro Di Leo
Docker
Python
AI
0.0 (0)09 Oct, 2025 232

python-iris-audio-query

Text queries over audio knowledge base

Y
Yu Han Eng
Docker
Python
AI
0.0 (0)05 Oct, 2025 201

InterSystems IRIS GraphRAG

GraphRAG with InterSystems IRIS

F
Fan Ji
Docker
Python
AI
4.0 (1)02 Oct, 2025 107

FHIR Data Explorer with Hybrid Search and AI Summaries

This is a POC to demonstrate how InterSystems IRIS can be used to interact with an external language via the Python SDK (IRIS Native) to create and analyze a FHIR repository. Finally, the data is visualized using Streamlit, featuring hybrid search to locate the patient and a local LLM model to generate a patient history based on the extracted data.

P
Pietro Di Leo
Docker
Python
AI
0.0 (0)09 Oct, 2025 270

RAGBookRecommender

A basic implementation of an AI book recommender using IRIS Vector search

G
Gabriel Ing
Python
AI
4.0 (1)20 Sep, 2025 70

customer-support-agent-demo

AI-powered customer support agent built with Python smolagents and InterSystems IRIS — SQL, RAG, and live interoperability

A
Alberto Fuentes
Docker
Python
AI
4.5 (1)29 Aug, 2025 164

DataAILite

DataAIlite.com – Secure in-memory analytics

I
Irina Yaroshevskaya
AI
0.0 (0)19 Aug, 2025 76

dc-artisan

Prompt & RAG Pipeline Toolkit for Developers

Docker
IPM
AI
5.0 (1)03 Aug, 2025 196 1

iris-vector-rag

Production-ready RAG applications with InterSystems IRIS.

Thomas Dyar
Docker
Python
AI
0.0 (0)23 Jul, 2025 219

☤ Care 🩺 Compass 🧭

RAG AI app for care managers, uses InterSystems IRIS as the Vector Store

B
Brad Nissenbaum
AI
5.0 (1)13 Jul, 2025 199

FHIRInsight

FHIRInsight: Transform complex health data into clear, actionable insights. A tool to convert FHIR blood test data into a comprehensive, easy-to-understand analysis report.

Docker
Python
IPM
AI
5.0 (1)31 May, 2025 320 8

ollama-ai-iris

Analyze PDF by extracting text and sending chat to ollama

O
Oliver Wilms
Docker
Python
AI
5.0 (1)24 May, 2025 146

iris-waveform-demo

Demo project storing HL7 timeseries (waveform) data in IRIS

A
Ajay Anand
Docker
4.0 (1)01 Apr, 2025 169